Keratin 8 (Ab-74) Antibody MBS9410153 from MyBioSource.com

Description

Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis

Product Specs
ItemKeratin 8 (Ab-74) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS9410153
Quantity0.025 ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
PurityAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide
ReactivityHuman
TargetKeratin 8
Molecular Weight56,608 Da
HostRabbit
ImmunogenThe antibody detects endogenous level of total Keratin 8 protein
NCBI Full Gene Namekeratin 8, type II
NCBI Gene AliasesKO, CYK8, CK-8, K2C8, CARD2, K8, CK8
ClonalityPolyclonal